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Urea is an organic chemical compound which essentially is the waste produced when the body metabolizes protein. It is produced when the liver breaks down protein or amino acids, and ammonia. The kidneys then transfer the urea from the blood to the urine. Concentrations of urea in blood can vary with diet, hepatic function, and numerous disease states. This test can be used to detect diseases and disorders that affect the kidneys, such as acute kidney failure or end-stage renal disease (ESRD). It also aids in the differential diagnosis of acute glomerulonephritis, chronic nephritis, tubular necrosis, and urinary tract obstruction. HIGH levels of serum urea indicate that the kidneys are not filtering properly.
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection.For alternative sample type, call the chemistry department.
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