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Troponin I is a part of the troponin complex. It is a contractile protein found almost solely in the myocardium. It is highly tissue-specific, and persists in the circulation for days. However, it is only detectable at 4 hours or more post injury. Troponin I elevation is useful for predicting in-hospital risk for unstable angina patients admitted to a community hospital. The association of ECG changes and HIGH troponin I identifies a population at very high risk; however, the absence of both variables in patients with a diagnosis of unstable angina does not preclude the development of events.
Use only fresh samples and avoid direct sunlight. Minimum sample volume is 2 mL. Stability 2 hours. Remove plasma from cells ASAP or within 2 hours of collection. Specimen must be free of particulate matter including fibrin which can interfere with the assay. Avoid transferring material from the white blood cell/platelet layer located just above the red blood cells
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