Under normal physiologic conditions, the usual daily dietary intake of aluminum is completely eliminated. Patients with renal failure lose the ability to clear aluminum and are candidates for aluminum toxicity. Aluminum overload leads to its accumulation in brain and bone resulting in dialysis dementia, secondary hyperparathyroidism, osteomalacia, microcytic anemia, and may contribute to the development of Alzheimer’s disease. INCREASED levels are seen in patients with metallic joint prosthesis, and hemodialysis patients who are exposed to aluminum-based phosphate binders.
Avoid hemolyzed samples