Immunoglobulin E (IgE) is one of the bodys five classes (isotypes) of immunoglobulins (antibodies). Like other immunoglobulins, IgE is produced by B cells and plasma cells. In contrast to other immunoglobulins, the concentration of IgE in the circulation is very low. Generally, adult IgE levels are achieved by 5 to 7 years of age. Between the ages of 10 and 14 years, IgE levels may be higher than those in adults. After age 70 years, IgE levels may decline slightly and be lower than the levels observed in adults younger than 40 years. The clinical utility of measuring IgE levels generally involves its role as the mediator of the allergic response. Other related tests: Allergen Specific IgE, Food and Inhalant Panels
Separate serum or plasma from cells ASAP or within 2 hours of collection.
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