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Hepatitis C Virus Total Antibodies, Serum

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HCV is a single-stranded RNA flavivirus. Six major HCV subtypes exist with varying amino acid sequences (genotypes); these subtypes vary geographically and in virulence and response to therapy. HCV can also alter its amino acid pattern over time in an infected person (producing quasispecies). Infection is most commonly transmitted through blood, primarily when parenteral drug users share needles, but also through tattoos or body piercing. Sexual transmission and vertical transmission from mother to infant are relatively rare. This test detects the presence of antibodies indicating exposure to HCV. Anti-HCV usually appears within 2 weeks of acute infection but is sometimes delayed. Symptoms of acute hepatitis C infection include decreased appetite, fatigue, abdominal pain, jaundice, itching, and flu-like symptoms. See Hepatitis C Virus (HCV) RNA, Quantitative, RT-PCR

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