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Anti-hepatitis B core antigen (anti-HBc) is an antibody to the hepatitis B core antigen. The core antigen is found on virus particles but disappears early in the course of infection. This antibody is produced during and after an acute HBV infection and is usually found in chronic HBV carriers as well as those who have cleared the virus, and usually persists for life. The detection of total HBcAb, indicates past infection, either acute or chronic. See Hepatitis Bc Antibodies, IgM, Serum; Hepatitis Bs Antigen (HBsAg), Serum; and Hepatitis B Virus (HBV) DNA Quantitative, PCR
Separate serum from cells ASAP