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Hemosiderin, Spot Urine

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Hemosiderin is an iron-storage complex (ferritin being the other). It is always found within cells (as opposed to circulating in blood) and appears to be a complex of ferritin, denatured ferritin and other material. The iron within deposits of hemosiderin is very poorly available to supply iron when needed. Several disease processes result in deposition of larger amounts of hemosiderin in tissues; although these deposits often cause no symptoms, they can lead to organ damage. Presence of hemosiderin in urine indicates a significant amount of circulating free hemoglobin that has been filtered by the kidney.

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