Copper is a component of many body proteins. It is an essential mineral that the body incorporates into enzymes. These enzymes play a role in the regulation of iron metabolism, formation of connective tissue, energy production at the cellular level, the creation of melanin, and the function of the nervous system and brain. About 95% of the copper in blood is bound to ceruloplasmin, therefore, test results are usually compared to ceruloplasmin levels. Copper levels are INCREASED in inflammation, cirrhosis, courses of estrogen, pregnancy, poisoning, and in conditions associated with severe malabsorption, such as cystic fibrosis and celiac disease. DECREASED levels are seen in nephrotic syndrome, Wilson’s disease, and Menkes’ syndrome.
Separate serum from cells as soon as possible. Avoid haemolysis.