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Cholesterol is a lipidic, waxy steroid found in the cell membranes and transported in the blood plasma. It is an essential component of cell membranes where it is required to establish proper membrane permeability and fluidity. Measurements of serum cholesterol levels are important in the diagnosis of hyperlipoproteinemias, and to estimate the risk of developing a heart disease (atherosclerosis). HIGH total cholesterol levels may occur with hypothyroidism, nephrotic syndrome, diabetes, biliary cirrhosis, familial hyperlipidemias, and high-fat diet. LOW levels are associated with hyperthyroidism, severe liver disease, malabsorption, malnutrition, pernicious anemia, and sepsis.
12 Hrs fasting preferred. For alternative sample type, call the chemistry department. Allow serum tube to clot completely at room temperature. Separate serum or plasma from cells within 2 hours of collection
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