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Bilirubin, a breakdown product of lysed red blood cells, is present in amniotic fluid in very small concentrations relative to serum. In an uncomplicated pregnancy, bilirubin in amniotic fluid peaks at 19-22 weeks of gestation. This test is used in the diagnosis of hemolytic disease of the fetus due to Rh incompatibility. INCREASED concentrations are associated with intrauterine hemolysis which, in turn, causes erythroblastosis fetalis.
Store sample refrigerated. State week of gestation. Result correlates to a specific curve.
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