Biolab is equipped with state of the art equipment and instruments and according to the most recent advancements in the laboratory industry.
Gene Sequencer ABI PRISM – 310 Genetic Analyzer
DNA Sequencing by Capillary Electrophoresis is the ideal alternative to gel-based DNA analysis for any research, clinical or forensic lab. The ABI PRISM® 310 Genetic Analyzer is an automated single-capillary genetic analyzer designed for a wide range of sequencing and fragment analysis applications. It performs comparative sequencing, linkage analysis, SNP detection, discovery and validation, mutation detection, and many other applications.
It allows rapid diagnosis of different diseases. It enables to automate applications from de novo sequencing to SNP validation and linkage mapping [RF1] . Examples of such applications are Amnio PCR for aneuploidy screening of chromosomes 13, 18, 21, X and Y, Duchenne and Becker Muscular Dystrophy and Fragile X.
COBAS TaqMan 48
The COBAS TaqMan 48 Analyzer is a real-time PCR analyzer that provides unmatched accuracy, flexibility, maximum efficiency, a superior dynamic range and contamination risk elimination. This method is mainly utilized for the monitoring and quantification of target copy numbers of viral load such as Hepatitis B and C Viruses. COBAS TaqMan 48 is one of the few worldwide FDA approved instruments.
Corbett Rotor-gene 6000
Real-time Polymerase Chain Reaction (PCR) is the ability to monitor the progress of the PCR as it occurs. It enables the detection of very small amounts of specific nucleic acid sequences during the early phases of the reaction and on a real-time basis. Data analysis, including standard curve generation and copy number calculation, is performed automatically. The Rotor-Gene is an innovative real-time cycler that enables high-precision real-time PCR. This instrument is usually utilized for the detection of infectious diseases.
Becton Dickinson FACSCalibur
The BD FACSCalibur™ flow cytometer is a versatile tool with enormous potential for the study of cells and particles. No other laboratory instrument provides multiparametric analysis at the single cell level, and the flow cytometer or application-variants of the flow cytometer will become more valuable as medical diagnosis and therapy changes. A flow cytometer can discriminate cells at speeds up to 70,000 cells/second. In addition to a high speed processing, this instrument offers high fluorescence sensitivity and minimal sample contamination. The BD FACSCalibur system can perform a wide range of complex tasks such as immunophenotyping, which is critical to the initial diagnosis and classification of the acute leukemias, chronic lymphoproliferative diseases, and malignant lymphomas. In addition, immunophenotyping provides prognostic information not available by other techniques, hence provides a sensitive means to monitor the progress of patients after chemotherapy or bone marrow transplantation, and often permits the detection of minimal residual disease. All these tasks are performed at biolab in addition to bone marrow transplantation and stem cell analysis, HIV infection (CD4/CD8) and many applications in research. This technique is used not only for complex tests performed in clinical laboratories, but also for life science and clinical research applications.
Applied Biosystems 9800 Fast Thermal Cycler
PCR (polymerase chain reaction) is a technique that is central to molecular biology research and diagnostics. The Applied Biosystems 9800 Fast Thermal Cycler (PCR) enables unmatched speed and performance, and provides reproducible, specific and sensitive PCR results. This is usually utilized in gene mutation amplification.
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